منابع مشابه
Aspirin and other anti-inflammatory drugs.
Historical introduction Salicylic acid, the active substance in plants used for thousands of years as medicaments, was synthesised by Kolbe in Germany in 1874. MacLagan and Stricker showed that it was eVective in rheumatic fever. A few years later sodium salicylate was also in use as a treatment for chronic rheumatoid arthritis and gout as well as an antiseptic compound. Felix HoVman was a youn...
متن کاملOther Studies Show Aspirin Use Is High
David Oaks I would like to thank PLoS Medicine for publishing Lacasse and Leo’s important and methodical Essay that debunks the “chemical imbalance” advertisements for psychiatric drugs [1]. Why would the United States Food and Drug Administration (FDA) approve such ads? Our human rights group, MindFreedom International, has been asking that question for a long time. On behalf of MindFreedom, U...
متن کاملAspirin and other nonsteroidal anti-inflammatory drugs and breast cancer incidence in a large U.S. cohort.
Use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly aspirin, has consistently been associated with reduced risk of breast cancer in case-control studies. However, results from prospective studies have been less consistent. We examined the association between NSAID use and breast cancer incidence, adjusting for multiple breast cancer risk factors among 77,413 women in the Cancer P...
متن کاملA large cohort study of aspirin and other nonsteroidal anti-inflammatory drugs and prostate cancer incidence.
BACKGROUND Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has consistently been associated with a reduced risk of colon cancer. Recent epidemiologic studies have suggested that the use of NSAIDs, particularly aspirin, may also be associated with a reduced risk of prostate cancer, but the evidence remains limited. METHODS We examined the association between NSAID use an...
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"Biotherapies" include both biopharmaceuticals and cell and gene therapies. Biopharmaceuticals are macromolecules created by biotechnologies. In the case of monoclonal antibodies, the starting dose to be given to Humans is difficult to select because there may be no relevant animal model. At the time of registration, the knowledge of the mechanism of action of monoclonal antibodies is insuffici...
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ژورنال
عنوان ژورنال: BMJ
سال: 2000
ISSN: 0959-8138
DOI: 10.1136/bmj.321.7270.1170